discovers new process for cells to repair DNA damage

 


🧬 Discovery of the DdrC Protein: A Natural DNA Repair Agent

Researchers at Western University in Canada have identified a protein named DdrC, found in the radiation-resistant bacterium Deinococcus radiodurans. This protein can independently repair DNA breaks by recognizing damage and signaling the cell to initiate repair processes. In laboratory tests, introducing DdrC into E. coli increased its resistance to UV radiation by up to 40 times. This discovery could pave the way for developing cancer vaccines or genetically engineered plants resistant to environmental stressors.
 
🧪 NEAT1 RNA: A Key Player in DNA Damage Response

A study published in Genes & Development has revealed that the long non-coding RNA NEAT1 plays a crucial role in DNA repair Under conditions of DNA damage, NEAT1 undergoes methylation changes that enable it to guide repair proteins to specific DNA lesions. This mechanism enhances the cell's ability to repair double-strand breaks, which are particularly challenging to fix. Manipulating NEAT1 levels could improve the effectiveness of treatments for conditions like cancer and neurodegenerative diseases.

🧠 TEX264 Protein: A Guardian Against DNA Damage

A collaborative study from the University of Sheffield and the University of Oxford has identified a protein called TEX264 that helps protect cells from DNA damage associated with aging and neurodegenerative diseases. TEX264 works by recognizing and removing toxic proteins that accumulate on DNA, preventing damage that could lead to conditions like motor neuron disease and cancer. This discovery offers new avenues for therapeutic strategies targeting DNA repair pathways.

🔬 Advanced Imaging Reveals DNA Repair Dynamics

Researchers have developed high-throughput imaging techniques to observe DNA repair in real-time at the single-cell level. These methods have uncovered that DNA repair proteins form "hubs" within cells, coordinating efforts to address DNA damage efficiently. Understanding these dynamics could lead to more precise interventions in cancer therapy and genetic disorders.

#DNADamage
#DNARepair
#GenomicStability
#CellBiology
#MolecularBiology
#CancerResearch
#GeneticDisorders
#RadiationBiology
#AgingResearch
#BiomedicalScience

World Cell Biologist Awards: 

Website Link : cellbiologist.org

Follow Us On : 
Tumblr ; tumblr.ccom/

Comments

Post a Comment

Popular posts from this blog

Guillain-Barré Syndrome Cases in Andhra Pradesh

Image
  Recently, the state of Andhra Pradesh has witnessed a rise in Guillain-Barré Syndrome (GBS) cases, prompting government action. The Chief Minister has ordered an investigation into the outbreak. Earlier this year, Maharashtra also reported rising cases of GBS. About Guillain-Barré Syndrome Guillain-Barré Syndrome (GBS) is a rare autoimmune disorder affecting the peripheral nervous system. GBS is characterised by muscle weakness and paralysis. It typically starts with weakness, tingling, or numbness in the limbs. Symptoms can progress rapidly, leading to paralysis that may last from six months to a year. The syndrome affects nerves responsible for muscle movement and sensation. While it can occur at any age, it is more common in adult males. Causes and Triggers The exact cause of GBS remains unknown. However, it often follows infections, either bacterial or viral. The immune system mistakenly attacks the body’s nerves after such infections. Some rare cases have been linked to va...
Read more

Bharat Cancer Genome Atlas

Image
  The Indian Institute of Technology Madras recently launched the Bharat Cancer Genome Atlas (BCGA). This initiative aims to enhance cancer research in India. It addresses the under-representation of Indian genetic data in global cancer studies. The launch comes ahead of World Cancer Day and marks the increasing cancer incidence in the country. Overview of the Bharat Cancer Genome Atlas The BCGA is a comprehensive database of genetic variants linked to breast cancer in India. It collects data from breast cancer patients across the country. The goal is to identify specific biomarkers for early detection and develop targeted treatment strategies. Significance of the Initiative This initiative is crucial for understanding the unique genetic landscape of Indian cancers. The database will aid in the identification of cancer-specific biomarkers. It will also facilitate the development of diagnostic kits and targeted therapies tailored to the Indian population. Research and Collaboration...
Read more

New Study Reveals Dire State of Global Fish Stocks

Image
  A recent study published in the journal Science has found that global fish populations are facing more serious problems than we previously thought, with more fish stocks being overfished or in danger of collapse. Key Findings The study shows that current fishing practices are taking more fish than can naturally be replenished, mainly due to both local and large-scale industrial fishing. Researchers looked at data from 230 different fish stocks and discovered that past reports had overestimated how many fish were available and how quickly they could recover. Issues with Catch Limits Policymakers set limits on how many fish can be caught based on scientific advice to prevent overfishing. However, these limits have often been set too high, which has resulted in nearly one-third of fish stocks labeled as “sustainably fished” by the FAO actually being overfished. What is “Phantom Recoveries”? The study also found cases of “phantom recoveries,” where fish populations appeared to be doi...
Read more