Stem cells reverse woman’s diabetes — a world first
The innovative treatment involved extracting fat cells from the patient and reprogramming them into pluripotent stem cells capable of developing into various cell types. These reprogrammed cells were then coaxed to differentiate into insulin-producing islet cells. Approximately 1.5 million of these islet cells were injected into the patient's abdominal muscles during a minimally invasive procedure. This approach allowed for continuous monitoring using magnetic resonance imaging (MRI), ensuring the safety and functionality of the transplanted cells.
Within 75 days post-transplant, the patient achieved insulin independence, with her blood glucose levels remaining within the target range for over 98% of the day. As of over a year later, she continues to produce insulin naturally, eliminating the need for insulin injections.
🌍 Global Implications
This advancement holds significant promise for the future of diabetes treatment. Experts view this as a major step toward developing personalized, long-term solutions for type 1 diabetes. The use of the patient's own cells minimizes the risk of immune rejection, a common challenge in organ transplants. However, researchers emphasize the need for further studies to assess the long-term safety and efficacy of this therapy.
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