What are Nanozymes?

 



Recent research focuses on artificial enzymes known as nanozymes, which show promise in creating advanced materials for medicine. Scientists aim to understand how nanozymes interact with proteins, goal is to develop nanozymes that are precise and efficient.

About Nanozymes

Nanozymes are synthetic enzymes that mimic natural enzyme functions, which can interact with small molecules but their role with larger proteins is less understood. Research is now expanding to include structural proteins, such as collagen.

Research at CSIR-CLRI

A team at the CSIR-Central Leather Research Institute investigated nanozymes’ interaction with collagen. Led by Dr. Amit Vernekar, the team used a manganese-based oxidase nanozyme (MnN). They demonstrated that MnN could crosslink collagen molecules effectively.

Crosslinking Process

Crosslinking involves linking collagen molecules together. The researchers used tannic acid under mild conditions. This method preserved the natural structure of collagen. It enhanced collagen’s stability, making it resistant to degradation by collagenase.

Artificial Enzyme Design

In another study, researchers embedded an active site in a material called MOF-808. This design mimics natural enzymes’ binding pockets. It improved control over chemical reactions. However, challenges arose with larger proteins like cytochrome c.

Balancing Reactivity

The study marks the need to balance desired and unwanted reactivity. This is crucial when designing artificial enzymes for medical applications. Careful design ensures selectivity and efficiency in enzyme interactions.

Expanding Applications

The research broadens nanozymes’ applications beyond small molecules. It paves the way for developing biomaterials with intact structural properties. Such advancements are essential for therapeutic uses and enhancing material durability.

The team’s work reveals how nanozymes can interact with structural proteins. It emphasizes the importance of careful design in creating artificial enzymes. These findings contribute to the fields of biotechnology and medicine.

#PolymeraseChainReaction
#PCRTechnique
#DNAAmplification
#MolecularBiology
#GeneticResearch
#DNASequencing
#Biotech
#ForensicScience
#DiseaseDiagnostics
#LabTech

World Cell Biologist Awards: 

Website Link : cellbiologist.org 
Nomination Link : cellbiologist.org/award-nomination/?ecategory=Awards&rcategory=Awardee Contact Us: contact@cellbiologist.org 

Follow Us On : 
Twitter : twitter.com/account/access
Blogger : blogger.com/u/1/blog/posts/1155994660171864058
Pinterest :pinterest.com/researchs625/?actingBusinessId=907757006050531250
Linkedin : .linkedin.com/in/research-scholar-10278a323/ 
Tumblr ; tumblr.com/

Comments

Post a Comment

Popular posts from this blog

Guillain-Barré Syndrome Cases in Andhra Pradesh

Image
  Recently, the state of Andhra Pradesh has witnessed a rise in Guillain-Barré Syndrome (GBS) cases, prompting government action. The Chief Minister has ordered an investigation into the outbreak. Earlier this year, Maharashtra also reported rising cases of GBS. About Guillain-Barré Syndrome Guillain-Barré Syndrome (GBS) is a rare autoimmune disorder affecting the peripheral nervous system. GBS is characterised by muscle weakness and paralysis. It typically starts with weakness, tingling, or numbness in the limbs. Symptoms can progress rapidly, leading to paralysis that may last from six months to a year. The syndrome affects nerves responsible for muscle movement and sensation. While it can occur at any age, it is more common in adult males. Causes and Triggers The exact cause of GBS remains unknown. However, it often follows infections, either bacterial or viral. The immune system mistakenly attacks the body’s nerves after such infections. Some rare cases have been linked to va...
Read more

Bharat Cancer Genome Atlas

Image
  The Indian Institute of Technology Madras recently launched the Bharat Cancer Genome Atlas (BCGA). This initiative aims to enhance cancer research in India. It addresses the under-representation of Indian genetic data in global cancer studies. The launch comes ahead of World Cancer Day and marks the increasing cancer incidence in the country. Overview of the Bharat Cancer Genome Atlas The BCGA is a comprehensive database of genetic variants linked to breast cancer in India. It collects data from breast cancer patients across the country. The goal is to identify specific biomarkers for early detection and develop targeted treatment strategies. Significance of the Initiative This initiative is crucial for understanding the unique genetic landscape of Indian cancers. The database will aid in the identification of cancer-specific biomarkers. It will also facilitate the development of diagnostic kits and targeted therapies tailored to the Indian population. Research and Collaboration...
Read more

New Study Reveals Dire State of Global Fish Stocks

Image
  A recent study published in the journal Science has found that global fish populations are facing more serious problems than we previously thought, with more fish stocks being overfished or in danger of collapse. Key Findings The study shows that current fishing practices are taking more fish than can naturally be replenished, mainly due to both local and large-scale industrial fishing. Researchers looked at data from 230 different fish stocks and discovered that past reports had overestimated how many fish were available and how quickly they could recover. Issues with Catch Limits Policymakers set limits on how many fish can be caught based on scientific advice to prevent overfishing. However, these limits have often been set too high, which has resulted in nearly one-third of fish stocks labeled as “sustainably fished” by the FAO actually being overfished. What is “Phantom Recoveries”? The study also found cases of “phantom recoveries,” where fish populations appeared to be doi...
Read more